Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep322 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Does hepatitis C virus (HCV) infection has a role in the pathogenesis of diabetes mellitus in patients with β thalassemia

De Sanctis Vincenzo , Soliman Ashraf , Candini Giancarlo , Elsedfy Heba

Introduction: In patients with β thalassemia major (TM) The interplay between liver siderosis and hepatitis C virus (HCV) infection may facilitates the progression to insulin resistance (IR) and diabetes mellitus (DM).Objectives: Many TM patients are infected with either HCV. Therefore, we aimed to explore if there is any association between DM and HCV-RNA positivity with different genotypes.Patients and methods: 148 TM patien...

ea0037ep651 | Pituitary: basic and neuroendocrinology | ECE2015

Assessment of GH–IGF1 axis in adults with beta-thalassemia major: when to do a GH stimulation test?

De Sanctis Vincenzo , Soliman Ashraf , Candini Giancarlo , Elsedfy Heba

GHD in adults (AGHD) is a clinical syndrome associated with lack of positive well-being, depressed mood, feelings of social isolation, decreased energy, alterations in body composition with reduced bone and muscle mass, diminished exercise performance, and cardiac capacity. These manifestations are also common in adults with beta-thalassemia major (BTM). Performing provocative testing in all patients is cumbersome and expensive. Many studies suggested that IGF1 may be used for...